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Accueil > Publications > Archives 2004-2010 > 2007

A microfluidic device based on droplet storage for screening solubility diagrams

P. Laval, N. Lisai, J.-B. Salmon, M. Joanicot — Lab Chip 7, 829 (2007)

publié le , mis à jour le

This work describes a new microfluidic device developed for the rapid screening of solubility diagrams. In several parallel channels, hundreds of nanolitre volume droplets of a given solution are first stored with a gradual variation in the solute concentration. Then, the application of a temperature gradient along these channels enables us to read directly and quantitatively phase diagrams, concentration vs. temperature. We show, using a solution of adipic acid, that we can measure ten points of the solubility curve in less than 1 hr and with only 250 µL of solution.